slither-locandinaA meteorite housing a malevolent alien parasite crashes into the town of Wheelsy, South Carolina. While frolicking in the woods with Brenda (James), local car dealer Grant Grant (Rooker) is subsequently infected by the parasite. The parasite takes over his body and absorbs his consciousness and memories.

With the alien now in control of his body, ‘Grant’ begins to slowly change into a hideous tentacular slug-like monster.

No one suspects Grant of the serial pet murders that have occurred around town, however his wife Starla (Banks) begins to question his health. He avoids doctors and lies to keep her in the dark. Sensing her distance from her husband, Starla contacts town sheriff Bill Pardy (Fillion) who attempts to reassure and comfort her while not acting on his feelings…