Jungle Jack is a playful puppy, a very rare species, and he spends his life in a jungle of Florida between fruit and a thousand jokes at the expense of his two friends and monkeys Zick Zack.

But one day his special appearance attracts the attention of Ghertrude, a wicked woman collector of animals looking for some rarities along with his surly assistant Coccomerone.

From that moment Jungle Jack must embark on a daring escape that will take him to New York.