A_Cuore_Aperto-locandinaRespected cardiac surgeon Dr. Thomas Vrain performs a risky operation to provide a patient with the first artificial heart ever implanted in a human subject.

He and his colleague, research scientist Dr. Aldo Gehring, consider the risks and weigh the odds as time runs out for Carol Severance, the patient.

Severence will die unless the experimental surgery is done quickly and succeeds.